The population of the City of Charlottesville in 1900, according to that year's census, was 6,449. According to the same census, the population of Albemarle County in 1900 was 28,473.
- May 24 – The 1900 election was for municipal officers in the city, in the county the vote was on the Convention, there being no officers. The majority in Albemarle County and Charlottesille voted for the Constitutional Convention. Virginia voters approved a proposed Constitutional Convention by state referendum. (An elected body of one hundred delegates, including eleven Republican and one Independent, convened in Richmond on June 12, 1901, and debated for almost a year, until June 26, 1902).
- November 6 – United States presidential election. Bryan carried the city (66.15%, 731 votes) and the county (67.72%, 2,411 votes). Virginia voted for the Democratic candidate, former U.S. Representative William J. Bryan over the Republican candidate, incumbent President William McKinley.
- August 11 – University of Virginia professor Charles Scott Venable, a mathematician, astronomer, and civil war military officer.